Status:

RECRUITING

PET TDM FDG-Choline as a Decision-making Tool for Routine Care on the Liver Transplant List for HCC

Lead Sponsor:

University Hospital, Lille

Conditions:

Hepatocellular Carcinoma

Liver Transplant

Eligibility:

All Genders

18+ years

Brief Summary

HCC is the most common malignant liver tumor for which liver transplantation is one of the pivotal curative treatments. The best possible selection of patients who are candidates for transplantation i...

Eligibility Criteria

Inclusion

  • Patient candidate for liver transplantation for hepatocellular carcinoma from the University Hospital of Lille and Rouen, whose therapeutic transplantation project has been validated and having an AFP score ≤ 2 (diagnosis of HCC defined on non-invasive imaging criteria according to the recommendations of EASL-EORTC 2012 or confirmed histologically).
  • No opposition to participating in the study.
  • Patient affiliated to a social security scheme

Exclusion

  • Patient with an AFP score ≥ 3
  • Patient contraindicated to PET FDG or Choline.
  • Other tumor: Cholangiocarcinoma.
  • Diabetes unbalanced HbA1c\> 9%, and fasting hyperglycemia (\> 2g / L) which does not allow the completion of the PET examination.
  • Patient under guardianship or curatorship.
  • Pregnant or breastfeeding woman.

Key Trial Info

Start Date :

June 22 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2028

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04792801

Start Date

June 22 2021

End Date

June 1 2028

Last Update

March 15 2022

Active Locations (1)

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Hop Claude Huriez Chu Lille

Lille, France, 59037