Status:
COMPLETED
Cortex Motor Function Reorganization in Stroke Patients
Lead Sponsor:
Guangzhou General Hospital of Guangzhou Military Command
Conditions:
Ischemic Stroke
Eligibility:
All Genders
18-75 years
Brief Summary
In China, stroke is among the highest morbidity and mortality, especially in senile population. Most of those patients had survived with various degrees of cerebral dysfunction; among them about 50% w...
Detailed Description
The cases derive from patients with acute ischemic stroke hospitalized in Neurology Department General Hospital of Guangzhou Military Command of PLA. The diagnosis of ischemic stroke is diagnosed usin...
Eligibility Criteria
Inclusion
- The first onset, the lesion was the single lesion of infarction or hemorrhage confirmed by head Magnetic Resonance Imaging(MRI) or Computed Tomography(CT).
- Hemiplegic hand muscle strength above grade 3, and was able to cooperate with the stimulation task of f MRI examination.
- According to the Edinburgh Handedness Questionnaire (EHQ) as the right hand.
- According to the commonly used eye chart examination, the naked eye vision \>4.9.
- There is no central nervous system organic disease and other motor diseases that can affect hand function.
- No previous long-term alcoholism and long-term use of central nervous system activity and other drugs treatment.
- No contraindication to MRI scan.
- The patient cooperated with the examination and the patient or their guardian signed an informed consent.
Exclusion
- Previous diseases of the central nervous system and peripheral nervous system that significantly affected the motor function of limbs.
- Significant cognitive impairment, MMSE≤27.
- Subjects was engaged in professional music playing or keyboard operation before illness.
- The level of consciousness drops after the illness.
- Significant anxiety and depression status (Hamilton anxiety scale ≥14 points, Hamilton depression scale ≥13 points) and other mental illness and history.
- Aphasia and neglect.
- History of epilepsy
- History of drug dependence
- Liver dysfunction, renal dysfunction, heart failure or other important organ function loss compensation
- Contraindication to MRI scan.
- Refuse to provide written consent or fail to cooperate with inspection for other reasons.
Key Trial Info
Start Date :
January 12 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 30 2020
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT04794673
Start Date
January 12 2020
End Date
August 30 2020
Last Update
March 12 2021
Active Locations (1)
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1
General Hospital of Southern Theatre Command,PLA
Guangzhou, Guangdong, China, 510010