Status:
UNKNOWN
Effects of Different Methods of PDAC Specimen Acquisition on Primary Cell Culture and Application
Lead Sponsor:
The Third Xiangya Hospital of Central South University
Conditions:
Pancreatic Ductal Adenocarcinoma
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to investigate the difference in the success rate of culturing primary cells derived from pancreatic ductal adenocarcinoma specimens of patients which obtained by endoscop...
Detailed Description
Pancreatic cancer is one of the malignant tumors with the highest mortality rate in the world, with a 5-year survival rate of only 7.2%-9%. Because some patients are resistant to multiple chemotherapy...
Eligibility Criteria
Inclusion
- Male or female, age≥18
- Imaging examination (US, MRI, CT or PET-CT) of patients confirmed pancreatic lesions, and considered the possibility of PDAC, EUS-FNB was needed for auxiliary diagnosis
- No chemotherapy, including neoadjuvant chemotherapy, postoperative adjuvant chemotherapy and palliative chemotherapy, has been performed on patients
- Having surgery opportunities (including radical operation and cytoreductive surgery) and willingness of operation
- Agree to attend this study and signed informed consent
Exclusion
- Poor physical condition, including but not limited to hemoglobin ≤ 8.0g/dl, severe cardiopulmonary insufficiency, etc
- Coagulation dysfunction (platelet count \< 50,000/mm3, international standardized ratio \> 1.5), or inability to discontinue anticoagulation therapy
- High risk for deep sedation
- Acute pancreatitis in the previous 2 weeks
- Pregnancy or lactation
- Any diseases leading to unreliable follow-up
- Absence of informed consent
Key Trial Info
Start Date :
January 15 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 28 2022
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04797676
Start Date
January 15 2021
End Date
February 28 2022
Last Update
March 15 2021
Active Locations (1)
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1
The Third Xiangya Hospital, Central South University
Changsha, Hunan, China, 410013