Status:

COMPLETED

HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy

Lead Sponsor:

Indiana University

Collaborating Sponsors:

Folia Health

Cystic Fibrosis Foundation

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

12+ years

Brief Summary

This is an observational cohort study, using data from Folia Health and the Cystic Fibrosis Foundation Patient Registry (CFFPR). Individuals taking elexacaftor/tezacaftor/ivacaftor (ETI) may be enroll...

Detailed Description

This study will be a prospective, observational cohort study to investigate the changes in lung function among individuals who have made treatment changes after initiating treatment with elexacaftor/t...

Eligibility Criteria

Inclusion

  • Written informed consent (and assent when applicable) obtained from subject or subject's legal guardian.
  • Is willing and able to adhere to protocol requirements.
  • ≥ 12 years of age at enrollment.
  • Diagnosed with CF.
  • Prescribed ETI for an on-label indication.
  • Participant has access to a mobile phone or tablet (iPhone or Android platform) or computer.
  • Participant has access to an internet connection.

Exclusion

  • Participant is enrolled in the randomized portion of the SIMPLIFY study (NCT04378153).
  • Participant does not have access to the necessary technology.
  • Participant is a recipient of a solid organ transplant (i.e. lung, liver, pancreas, kidney).
  • Participant cannot communicate in English.

Key Trial Info

Start Date :

May 26 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 15 2023

Estimated Enrollment :

860 Patients enrolled

Trial Details

Trial ID

NCT04798014

Start Date

May 26 2021

End Date

August 15 2023

Last Update

May 2 2024

Active Locations (1)

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Indiana University School of Medicine

Indianapolis, Indiana, United States, 46202