Status:

UNKNOWN

Expression of CXCR4 in Patients With Systemic Lupus Erythematosus

Lead Sponsor:

Sohag University

Conditions:

Systemic Lupus Erythematosus

Eligibility:

All Genders

16-60 years

Brief Summary

The objective of this study is to estimate the possible role of CD184 in the pathogenesis of SLE; comparing its level among SLE cases to healthy controls.

Detailed Description

Detection of CXCR4 (CD184) expression on CD19+ B cells by flow cytometry in patients of SLE, comparing its level in the development of lupus activity and pathogenic process of SLE internal organ invol...

Eligibility Criteria

Inclusion

  • Confirmed SLE patients diagnosed and fulfilled the SLE classification criteria according to the 2019 ACR/EULAR classification criteria for SLE (Aringer et al., 2019)
  • Willing and agreed to be included in the study.

Exclusion

  • Childhood SLE.
  • SLE-patients will refuse to consent to this study.
  • Other autoimmune diseases.
  • Known or suspected malignancies, especially B cell lymphoma.

Key Trial Info

Start Date :

May 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04799730

Start Date

May 1 2021

End Date

May 1 2022

Last Update

March 16 2021

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