Status:
UNKNOWN
Endoscopic Ultrasound Guided Coeliac Plexus Neurolysis for Cancer Pain
Lead Sponsor:
The University of Hong Kong
Conditions:
Malignancy
Pain Management
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Many cancer patients suffer from intractable pain and which is often suboptimally controlled by even strong opioid analgesics. Coeliac plexus neurolysis (CPN) is procedure which intended to permanentl...
Detailed Description
The aim of this study is to compare the efficacy of EUS-CPN by chemical ablation using alcohol injection versus by radiofrequency ablation in patients with cancer pain related to intra-abdominal malig...
Eligibility Criteria
Inclusion
- Age ≥18 year-old
- Patients who give informed consent to the study
- Suboptimal pain control with regular analgesics
- Inoperable cancer of pancreas, biliary system and liver (both primary or secondary)
Exclusion
- Patients who refuse to give consent
- Patients aged \<18 years
- EUS not possible due to:
- Problem related to scope insertion such as trismus, stenosis of the upper GI tract
- Coagulopathy with INR \>1.5 or platelet count \< 70
- Low oxygen saturation or extreme blood pressure render endoscopic procedure unsafe
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 31 2025
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT04801082
Start Date
March 1 2021
End Date
March 31 2025
Last Update
March 22 2021
Active Locations (1)
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1
The University of Hong Kong
Hong Kong, Hong Kong, 000000