Status:
UNKNOWN
In Vivo Assessment of Geno- and Cytotoxicity of Fluoridated Toothpastes and Mouthrinses on Buccal Epithelial Cells
Lead Sponsor:
University of Split, School of Medicine
Conditions:
DNA Damage
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Buccal cells represent the first barrier to the oral hygiene products' potential toxic effect. The usual concentration of fluoride in toothpastes is 1000/1100 parts per million (ppm F); toothpastes wi...
Eligibility Criteria
Inclusion
- healthy subjects
- a sufficient level of education to understand the procedures
- patients not younger than 18 and not older than 65 years
- non-smokers
- patients without exposure to any x-ray examination in last 6 months
Exclusion
- subjects with use of any medications
- subjects that use alcohol
- subjects with oral lesions
- subjects with history of chronic health conditions
Key Trial Info
Start Date :
January 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04801576
Start Date
January 1 2021
End Date
July 31 2023
Last Update
January 28 2022
Active Locations (1)
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1
University of Split School of medicine
Split, Croatia, 21000