Status:
UNKNOWN
Elective Internal Mammary Node Irradiation in Women With Node-positive Breast Cancer
Lead Sponsor:
Yonsei University
Conditions:
Breast Neoplasms
Eligibility:
FEMALE
18+ years
Phase:
PHASE3
Brief Summary
The aim of this study is to find out whether the inclusion of internal mammary node irradiation in regional nodal irradiation improves outcomes in women with node-positive breast cancer.
Detailed Description
This is a multicenter, prospective, randomized phase 3 trial. Patients with node-positive breast cancer without distant metastases were included. All patients underwent breast conservation surgery or ...
Eligibility Criteria
Inclusion
- 1\. Women with histologically confirmed node-positive breast cancer who had undergone modified radical mastectomy or breast-conserving surgery and axillary dissection with ≥8 nodes removed.
Exclusion
- Neoadjuvant chemotherapy
- Bilateral breast cancer
- Distant metastasis
- History of other malignancy
- Involvement of supraclavicular nodes or internal mammary nodes at diagnosis
Key Trial Info
Start Date :
November 5 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2023
Estimated Enrollment :
747 Patients enrolled
Trial Details
Trial ID
NCT04803266
Start Date
November 5 2008
End Date
February 1 2023
Last Update
March 17 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Yonsei Severance Hospital
Seoul, South Korea