Status:
COMPLETED
Tube Feeding in Children Having a Bone Marrow Transplant
Lead Sponsor:
Institute of Child Health
Collaborating Sponsors:
National Institute for Health Research, United Kingdom
Great Ormond Street Hospital for Children NHS Foundation Trust
Conditions:
Bone Marrow Disease
Stem Cell Transplant Complications
Eligibility:
All Genders
1-13 years
Brief Summary
The purpose of this study is to assess the problems and a range of nutritional and clinical outcomes that occur with two feeding tubes used by children having a bone marrow transplant. Children and pa...
Detailed Description
Background: Bone marrow transplant (BMT) is the only potentially curative treatment for children with malignant and non-malignant diseases. Chemotherapy provided during BMT causes side-effects includi...
Eligibility Criteria
Inclusion
- Admitted to the centre during the study period for an allogeneic bone marrow transplant (BMT) for any diagnosis.
- Receiving any conditioning regimen, donor type and stem cell source.
- Children admitted for their second or more BMT.
- Children admitted on an established enteral tube feeding regimen.
- NHS patients.
Exclusion
- Children receiving first-line, prophylactic, parenteral nutrition as this is not the standard nutrition pathway of most children receiving BMT at the centre. This is usually given in specific circumstances such as children receiving cord blood transplants or those with gastrointestinal diseases.
- Autologous BMT, including children receiving chimeric antigen receptor T-cell therapy (CAR-T).
- No feeding tube placed and no nutrition support required from tube feeding or parenteral nutrition. Children rarely do not require any form of nutrition support.
Key Trial Info
Start Date :
March 15 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2023
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT04804631
Start Date
March 15 2021
End Date
May 1 2023
Last Update
April 4 2024
Active Locations (1)
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1
Great Ormond Street Hospital
London, United Kingdom, WC1N3JH