Status:
UNKNOWN
SodiUm Restriction by Behavioral Intervention
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University
Conditions:
IgA Nephropathy
Eligibility:
All Genders
14-70 years
Phase:
NA
Brief Summary
The aim of this study is to evaluate the effects and efficacy of dietary sodium restriction by mean of a new healthcare approach in patients with immunoglobulin A nephropathy. The test persons in the ...
Detailed Description
Patients in the intervention group receive regular sodium-restriction education by a dietician, which entails introducing food types and cooking skills, quantifying salt intake with a special spoon an...
Eligibility Criteria
Inclusion
- Female or male patients\>14 years of age and \<70 years of age
- Diagnosed immunoglobulin A nephropathy with biopsy;
- eGFR\>30ml/min per 1.73m2 using Chronic Kidney Disease Epidemiology Collaboration formula
- Proteinuria \>1 g per day
- urinary sodium excretion \>200 mmol per day within one month
- systolic blood pressure higher than 140 mmHg or diastolic blood pressure higher than 90 mmHg, or a well-controlled blood pressure by treatment with antihypertensives including renin-angiotensin-aldosterone system-blockade (ACE-inhibitor or ARB)
- Written informed consent
Exclusion
- Be treated with diuretics
- Blood pressure \> 180 mmHg systolic or \> 125 mmHg diastolic without medical treatment
- Have undergone renal transplantation
- With acute kidney injury (RIFLE criteria) \< 6 months ago
- Cardiovascular or cerebrovascular event (myocardial infarction, cerebral hemorrhage or infarction) \< 6 months ago
- With progressive malignancy or pregnancy
- With contraindications of RAAS blockers
- unwilling or unable to meet the requirements of the protocol
Key Trial Info
Start Date :
May 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
142 Patients enrolled
Trial Details
Trial ID
NCT04805047
Start Date
May 15 2021
End Date
December 1 2023
Last Update
April 28 2022
Active Locations (1)
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1
First affiliated hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710061