Status:

COMPLETED

A Difference-In-Differences Analysis of New Persistent Opioid Use After Surgery

Lead Sponsor:

University of Michigan

Conditions:

Opioid Use

Eligibility:

All Genders

18+ years

Brief Summary

The Michigan Opioid Prescribing and Engagement Network (M-OPEN) was established in 2016 with the goal of reducing excessive opioid prescribing after surgery using evidence-based prescribing guidelines...

Detailed Description

In the United States, surgical care has become a gateway for chronic opioid dependence and its associated morbidity. Between 5-10% of patients who receive opioids for postoperative pain control go on ...

Eligibility Criteria

Inclusion

  • Adult patients (18 years and older)
  • Patients undergoing one of the following procedures: laparoscopic cholecystectomy, laparoscopic appendectomy, minor hernia repair (including laparoscopic or open inguinal, femoral, umbilical, and epigastric hernia repair), open and laparoscopic ventral/incisional hernia repair, laparoscopic colectomy, open colectomy, vaginal hysterectomy, laparoscopic hysterectomy, and open abdominal hysterectomy
  • Patients who underwent surgery between January 1, 2013 and December 31, 2019

Exclusion

  • Patients who are not opioid-naive at the time of surgery, defined as filling 1 or more opioid prescriptions between the 12 months to 31 days prior to surgery
  • Patients without continuous insurance enrollment for at least 12 months before and at least 6 months after the date of surgery
  • Patients still in the hospital on postoperative day 30
  • Patients not discharged home after surgery
  • Patients who underwent another surgery within 6 months of their index operation

Key Trial Info

Start Date :

January 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2019

Estimated Enrollment :

30000 Patients enrolled

Trial Details

Trial ID

NCT04805229

Start Date

January 1 2013

End Date

December 31 2019

Last Update

March 18 2021

Active Locations (1)

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1

University of Michigan

Ann Arbor, Michigan, United States, 48109