Status:
UNKNOWN
Nitric Oxide During Cardiopulmonary Bypass in Adult Surgery
Lead Sponsor:
Rabin Medical Center
Conditions:
Hypoxia
Eligibility:
All Genders
18-120 years
Phase:
PHASE3
Brief Summary
Inhaled nitric oxide is a widely accepted standard of care for pulmonary hypertension, and has been studied in the context of cardiac surgery. CPB during cardiac surgery induces systemic inflammatory ...
Detailed Description
This prospective, single center, double blinded, interventional trial will be conducted at Rabin Medical Center Beilinson Hospital. Adult patients undergoing CABG and valve replacement/ repair surgeri...
Eligibility Criteria
Inclusion
- Patients undergoing elective CABG surgeries with CPB at Rabin Medical Center Beilinson hospital.
- Patients undergoing valve replacement/repair surgeries with CPB at Rabin Medical Center Beilinson hospital.
Exclusion
- Patients requiring ECMO use preoperatively.
- Patients requiring IABP use preoperatively.
- Patients experiencing preoperative shock (defined as the need for ionotropic and/or vasopressor support).
- Patients after solid organ transplant surgery.
- Patients with LVAD.
- Patients with ESRD requiring dialysis preoperatively.
- Patients with a language barrier.
- Patients unable to give informed consent.
- Patients with heparin induced thrombocytopenia.
Key Trial Info
Start Date :
August 14 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2023
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04807413
Start Date
August 14 2021
End Date
May 1 2023
Last Update
October 8 2021
Active Locations (1)
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1
Rabin Medical Center/Beilinson Campus
Petah Tikva, Israel, 49100