Status:

WITHDRAWN

Adjunctive CB1 Agonist Nabilone in Inpatients With Active Suicidal Ideation

Lead Sponsor:

The University of Texas Health Science Center, Houston

Conditions:

Suicidal Ideation

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

Suicide is a major crisis worldwide with rates projected to continue to increase. There is currently a dearth of novel pharmacologic treatment options for suicide available on the market. The endocann...

Eligibility Criteria

Inclusion

  • Able to provide written informed consent
  • Current suicidal ideation
  • Columbia Suicide Severity Rating Scale (CSSRS) score of ≥ 4 and Scale for Suicide Ideation (SSI) first 5 items, score of ≥4
  • Current major depressive episode as evidenced by MADRS score ≥ 20

Exclusion

  • Current diagnosis of a Diagnostic and Statistical Manual V (DSM-V) psychotic disorder, psychotic symptoms, or personality disorder.
  • Recent (\<72 hrs) use of illicit substances
  • Comorbid substance use disorder diagnosis
  • Urine drug screen (UDS) positive for tetrahydrocannabinol (THC)
  • Pregnant or nursing women
  • Unstable medical condition

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2022

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04807829

Start Date

April 1 2021

End Date

April 1 2022

Last Update

September 22 2021

Active Locations (1)

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1

Harris County Psychiatric Center (HCPC)

Houston, Texas, United States, 77021