Status:
RECRUITING
Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer
Lead Sponsor:
Fudan University
Conditions:
Stomach Neoplasms
Endoscopy
Eligibility:
All Genders
18-75 years
Brief Summary
This study aims to test the hypothesis that the diagnosis for histological type, histological grade, LAUREN type, HER-2 expression, MSI/dMMR status, and EBV status in gastric cancer is at least as rel...
Detailed Description
Most institutions currently diagnose gastric cancer on endoscopic biopsy specimens but use surgical resection specimens for histological type, histological grade, LAUREN type, HER-2 expression, MSI/dM...
Eligibility Criteria
Inclusion
- Lower age limit of research subjects 18 years old and upper age limit of 75 years old.
- Histologically proven primary gastric adenocarcinoma (Diagnostic biopsies must be collected within 12 months prior to enrollment).
- Written informed consent from the patient.
- Patients planned for radical R0 gastrectomy.
Exclusion
- Female in pregnancy or lactation.
- Patients with gastric cancer who can not undergo tumor resection
- Suffering from other serious diseases, including cardiovascular, respiratory, kidney, or liver disease, complicated by poorly controlled hypertension, diabetes, mental disorders or diseases.
- Patients with poor compliance or considered to be poor compliance.
- Patients received any anticancer drugs, biotherapy, radiotherapy or immunotherapy within 4 weeks before or after enrollment.
- Patients after organ transplantation, long-term need to take immunosuppressants, autoimmune diseases.
Key Trial Info
Start Date :
May 24 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
510 Patients enrolled
Trial Details
Trial ID
NCT04809025
Start Date
May 24 2021
End Date
September 1 2026
Last Update
September 29 2025
Active Locations (1)
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1
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, China, 200000