Status:

UNKNOWN

Human Milk Fortification With Adjustable Versus Targeted Method

Lead Sponsor:

University of Calgary

Conditions:

Growth Failure

Eligibility:

All Genders

Phase:

NA

Brief Summary

Research question: Do preterm infants born \<1250 g achieve better weight gain with targeted fortification compared with the adjustable fortification of human milk? Hypothesis: Targeted fortification...

Detailed Description

Human milk is the ideal diet for neonates. However, it does not provide enough energy, protein, and sodium to meet the nutritional requirements of very preterm infants. Postnatal growth failure is com...

Eligibility Criteria

Inclusion

  • Infants with birth weight \<1250 g born at Foothills Medical Centre.
  • Appropriate for gestational age (AGA) (according to Fenton's Charts).

Exclusion

  • Abnormal Newborn Metabolic Screen
  • Major congenital anomalies intervention.
  • Patients who develop NEC prior to enrollment.
  • Patients with confirmed congenital Toxoplasmosis, Syphilis, Rubella, Cytomegalovirus, Herpes simplex virus, Varicella and/or Zika (TORCH infections).
  • Patients receiving systemic steroids.
  • Patients with acute kidney injury (AKI).

Key Trial Info

Start Date :

November 10 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 31 2025

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT04809350

Start Date

November 10 2023

End Date

May 31 2025

Last Update

November 30 2023

Active Locations (1)

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1

Foothills Medical Centre

Calgary, Alberta, Canada, T2N2T9