Status:

ACTIVE_NOT_RECRUITING

A Study of CDPATH™ to Help Manage and Treat Crohn's Disease

Lead Sponsor:

Takeda

Conditions:

Crohn's Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

CDPATH™ is a tool to help predict the potential for developing Crohn's disease related complications in certain adult participants within 3 years. The main aim of the study is to explore the use of CD...

Detailed Description

The tool being tested in this study is called CDPATH™. CDPATH™ is being used to provide a graphical representation of an individual participant's risk of developing a CD-related complication within th...

Eligibility Criteria

Inclusion

  • Has an initial diagnosis of CD established within five years prior to screening by clinical and endoscopic evidence and corroborated by a histopathology report (if available).
  • Has agreed to use the CDPATH™ tool.
  • Has reliable access to the internet and is willing to answer electronic patient-reported outcomes (ePROs) throughout the study.

Exclusion

  • Has had known complications from CD including but not limited to: bowel stricture, CD-related intra-abdominal abscess, internal penetrating disease (known fistula other than perianal fistula), non-perianal surgery, bowel resection, or stricturoplasty. A perianal fistula or abscess without other signs of penetrating disease is allowed.
  • Has had any non-CD-related abdominal surgery.
  • Has received investigational biologic or nonbiologic agents for the treatment of CD in an investigational protocol. Approved biologic or nonbiologic agents for CD are allowed.
  • Has previously used CDPATH™ or PROSPECT results to assess CD risk for complications.

Key Trial Info

Start Date :

June 25 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 12 2026

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04809363

Start Date

June 25 2021

End Date

September 12 2026

Last Update

November 5 2025

Active Locations (44)

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Page 1 of 11 (44 locations)

1

Arizona Arthritis & Rheumatology Research, PLLC

Phoenix, Arizona, United States, 85032

2

VA Loma Linda Healthcare System

Loma Linda, California, United States, 92357

3

United Medical Doctors

Murrieta, California, United States, 92563

4

University of Southern California Medical Center

Newport Beach, California, United States, 92663