Status:
TERMINATED
Comparing Immune Responses to Topical Imiquimod
Lead Sponsor:
University of California, Davis
Conditions:
Actinic Keratoses
Eligibility:
All Genders
18-85 years
Brief Summary
The study is a basic science research study that is designed to characterize and compare the immune response in individuals who are designated as ABO blood group secretors, meaning they have a functio...
Eligibility Criteria
Inclusion
- Individuals between 18 to 85 years of age
- Patients with a diagnosis that will result in treatment with imiquimod as standard of care, specifically actinic keratosis
Exclusion
- Younger than 18 years or older than 85 years.
- History of hypersensitivity/ allergic reaction or adverse reaction to imiquimod
- Individuals with a diagnostic biopsy and supportive histology of a cutaneous immune-mediated disease (e.g. psoriasis and mycosis fungoides, etc.) or diseases of the hematopoietic system, liver and the gastrointestinal tract (e.g. aplastic anemia, Crohn's disease, Ulcerative Colitis, Primary Sclerosing Cholangitis (PSC), Primary Biliary Cirrhosis, acute and chronic graft versus host disease (GVHD)).
- Individuals with autoantibodies plus objective evidence of end organ damage related to a cutaneous immune-mediated disease (e.g. psoriasis and mycosis fungoides, etc.) or diseases of the hematopoietic system, liver and the gastrointestinal tract (e.g. aplastic anemia, Crohn's disease, Ulcerative Colitis, Primary Sclerosing Cholangitis (PSC), Primary Biliary Cirrhosis, acute and chronic graft versus host disease (GVHD)).
- Individuals with a history of serious infection within the last 6 months.
- Individuals with tuberculosis, HIV, or hepatitis B, or C.
- Patients unable to provide consent
- Incarcerated individuals
Key Trial Info
Start Date :
March 16 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 7 2023
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT04809662
Start Date
March 16 2021
End Date
November 7 2023
Last Update
November 7 2024
Active Locations (1)
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1
University of California Davis
Sacramento, California, United States, 95816