Status:
COMPLETED
Effect of Progressive Early Mobilization in Patients With TBI
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Early Waking
Trauma
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
traumatic brain injury (TBI) is a major public health concern worldwide. Patients with moderate-severe TBI have high rates of disability at the acute phase and frequently require protracted rehabilita...
Detailed Description
Objective: The goals of this proposed research study are (1) to investigate the feasibility of using a structured progressive EM protocol for patients with moderate-severe TBI in a trauma ICU and (2) ...
Eligibility Criteria
Inclusion
- Expected to stay for at least 72 hours in the ICU,
- \>20 years of age with living independently before the onset of critical illness
- relatively stable vital signs with a Glasgow Coma Scale (GCS) score of ≥6
- relatively stable respiratory status (SpO2 \>92%, high mechanical ventilator setting: FiO2 ≤60%, and positive end-expiratory pressure ≤10 cmH2O)
- stable cardiovascular system (resting heart rate ≤130 bpm or no use of high-dose vasopressor of more than 0.2 μg kg-1 min-1)
Exclusion
- predicted mortality within the next 24 hours
- palliative care
- consistent increase of intracranial pressure (\>20 mmHg)
- pregnancy
- uncontrolled seizure
- active bleeding
- ruptured or leaking aortic aneurysm
- development of acute myocardial infarction during ICU stay
- rapid development of degenerative neuromuscular diseases
- contraindication for early walking
Key Trial Info
Start Date :
March 30 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 17 2024
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT04810273
Start Date
March 30 2021
End Date
January 17 2024
Last Update
February 6 2024
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 110