Status:
COMPLETED
The Effect of Functional Dairy Products Enriched With Dietary Fibers on Human Health and Gut Microbiota
Lead Sponsor:
Center of Food and Fermentation Technologies
Collaborating Sponsors:
SYNLAB Eesti OÜ, Tallinn, Estonia
AS FARMI Piimatööstus, Jõhvi, Estonia
Conditions:
Healthy
Eligibility:
All Genders
25-55 years
Phase:
NA
Brief Summary
The purpose of this dietary intervention is to study the effects of dietary fibers on the gut microbiota and use yoghurt as the carrier. Hypothesis 1: Intake of dietary fibers improves the blood lipi...
Detailed Description
The study design is a parallel randomized, prospective, pre-post intervention trial. The main goal of this study is to investigate the effect of the dietary fibers in an unsweetened yoghurt. Fermented...
Eligibility Criteria
Inclusion
- Age 25-55
- Normal bowel function
- Regular consumer of dairy products, willing to consume dairy products daily for 2 weeks
- Ability to provide a signed written informed consent
- Willing to provide stool and blood specimens 2 times over the 2-week study period
Exclusion
- Diagnosed history of chronic diseases including coronary heart disease, stroke, cancer, type 1 or 2 diabetes mellitus, inflammatory bowel disease, gastritis, autoimmune disease, or rheumatoid arthritis
- Medication: statins, blood pressure medications, antidepressants, other prescription medications
- History of bariatric operation, removal of the gallbladder.
- Food allergies, lactose intolerance
- Recent (previous 3 months) use of antibiotics
- Intake of highly dosed pre- or probiotics 2 weeks prior and during the study
- Current pregnancy or breastfeeding
- Volunteers showing previously unrecognized illness will also be excluded
- Individual unable to give informed consent
Key Trial Info
Start Date :
April 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2020
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT04811157
Start Date
April 1 2020
End Date
August 31 2020
Last Update
March 23 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Center of Food and Fermentation Technologies
Tallinn, Harju, Estonia, 12618