Status:
ACTIVE_NOT_RECRUITING
PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome
Lead Sponsor:
Michael Fredericson, MD
Conditions:
Carpal Tunnel Syndrome
PRP
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study assesses the potential benefit of adjuvant platelet-rich plasma (PRP) with carpal tunnel release (CTR) for patients with severe carpal tunnel syndrome (CTS). CTR is a rather common procedur...
Detailed Description
1. Study team recruits patients with severe CTS who meet inclusion and exclusion criteria in an outpatient hand surgery clinic. Patients will be consented by the research team if the patient agrees to...
Eligibility Criteria
Inclusion
- Adult age 18 years and up.
- Diagnosed with severe CTS based on EMG/NCS, meaning those with evidence of axonal loss (absent or low amplitude median sensory nerve action potential and/or absent or low amplitude median motor nerve action potential and/or evidence of abnormal spontaneous activity, reduced recruitment, or motor unit action potential changes on needle EMG of median innervated muscles).
Exclusion
- Younger than age 18 years (minor status).
- Diagnosed with concomitant peripheral neuropathy.
- Previous CTR on the affected side.
- Have contraindications to PRP (platelet dysfunction syndrome, critical thrombocytopenia, hemodynamic instability, septicemia, local infection at site of procedure, consistent use of NSAIDs within 48 hours of procedure, steroid injection at treatment site within 1 month, systemic use of steroids within 2 weeks, tobacco use, recent fever or illness, or cancer).
Key Trial Info
Start Date :
October 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 28 2026
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT04811287
Start Date
October 15 2021
End Date
December 28 2026
Last Update
April 21 2025
Active Locations (1)
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1
Stanford University
Redwood City, California, United States, 94063