Status:
RECRUITING
Prevention of Low Blood Pressure After Cardiac Surgery in Heart Failure Patients With a Filter Called CytoSorb.
Lead Sponsor:
Leiden University Medical Center
Conditions:
Heart Failure
Vasoplegia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Vasoplegia is a common complication after heart surgery for heart failure. With vasoplegia, the blood vessels can no longer squeeze properly, causing low blood pressure that is sometimes difficult to ...
Detailed Description
The incidence and prevalence of chronic heart failure is increasing. Despite the expansion of therapeutic options, overall survival and quality-of-life remain poor. When optimal medical therapy and ca...
Eligibility Criteria
Inclusion
- Diagnosed with HF in line with the European Society of Cardiology (ESC) guidelines34;
- Left ventricular EF ≤35%;
- Undergoing cardiac surgery on CPB with an anticipated duration of \>120 minutes;
- Age ≥18 years.
Exclusion
- Incapacitated;
- Emergency operation;
- Need for moderate or high dosages of intravenous inotropic support (\>4 gamma dobutamine or dopamine) and/or vasopression;
- Severe tricuspid regurgitation;
- Daily use of nitroglycerine or isosorbide dinitrate;
- Use of alpha blockers;
- Being heparin-induced thrombocytopenia (HIT) positive and citrate regional anticoagulation is unavailable as an alternative anticoagulation method;
- Platelet count \<20,000/μL.
Key Trial Info
Start Date :
October 27 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2026
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT04812717
Start Date
October 27 2021
End Date
January 31 2026
Last Update
December 13 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Leiden University Medical Center
Leiden, Netherlands