Status:
COMPLETED
Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA
Lead Sponsor:
University of Pennsylvania
Conditions:
Chronic Post-Surgical Pain
Eligibility:
All Genders
22+ years
Phase:
NA
Brief Summary
A significant number of patients develop chronic post-surgical pain (CPSP) following knee replacement surgery. Proposed is the testing of a novel computer-assisted behavioral intervention integrating ...
Detailed Description
A significant number of patients develop chronic post-surgical pain following knee joint replacement surgery, and the risk factors for this problematic outcome have been identified. Proposed is the de...
Eligibility Criteria
Inclusion
- Males and females, age \> 21 years
- Chronic non-malignant pain of at least 3 months duration
- Morphine equivalent daily dose (MEDD) \> 40 milligrams for at least 3 months
- Able to enroll at least 4 weeks prior to planned surgery
- Able to speak, read and comprehend in English at the 6th grade or higher proficiency
Exclusion
- Pain of malignant origin
- Current or past history of opioid use disorder (including those on medication-assisted therapy)
- Revision of TKA
- Comorbid CNS disease such as dementia, HIV, psychosis, poorly controlled bipolar disorder or any condition interfering with informed consent
Key Trial Info
Start Date :
October 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT04814992
Start Date
October 1 2020
End Date
December 31 2023
Last Update
October 17 2024
Active Locations (4)
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1
Penn Medicine University City
Philadelphia, Pennsylvania, United States, 19104
2
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, United States, 19104
3
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States, 19129
4
Penn Medicine Radnor
Radnor, Pennsylvania, United States, 19087