Status:
COMPLETED
Ketofol for Preventing Postoperative Delirium in Elderly Patients
Lead Sponsor:
Zagazig University
Conditions:
Delirium on Emergence
Eligibility:
All Genders
60+ years
Phase:
PHASE4
Brief Summary
* Delirium is a cognitive disturbance characterized by acute and fluctuating impairment in attention and awareness. Although its incidence in the general surgical population is 2-3%, it has been repor...
Detailed Description
Small bowel obstruction (SBO) is one of the most frequent causes of general emergency surgery in elderly patients, approximately 10-12% of adult patients above 65 years presenting with acute abdominal...
Eligibility Criteria
Inclusion
- Patient acceptance.
- Age ≥ 60 years old.
- American society of anesthesia (ASA) (II-III).
- Gender: males \&females
- BMI \< 35kg/m2.
- able to communicate verbally.
- Scheduled for exploration surgery for intestinal obstruction under general anesthesia of at least 60 min duration
Exclusion
- Patient refusal.
- Patients with delirium prior to surgery.
- Patients with drug misuse history or taking anti-psychotic drugs.
- Previous hospitalization within 3 months.
- Legal blindness, severe deafness.
- History of Acute cerebrovascular conditions; stroke or transient ischemic attack.
- Patients who could not be prepared with proper fluid resuscitation, electrolyte and acid-base correction prior to surgery.
- Patients who could be discharged from the intensive care unit (ICU) within two days.
- Patients with a known history of allergy to study drugs
Key Trial Info
Start Date :
March 25 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2023
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04816162
Start Date
March 25 2021
End Date
February 1 2023
Last Update
August 1 2023
Active Locations (1)
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1
Faculty of medicine, zagazig university
Zagazig, Alsharqia, Egypt, 4115