Status:

COMPLETED

Silymarin in COVID-19 Patients Admitted to Hospital With Elevated Liver Enzymes

Lead Sponsor:

F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica

Conditions:

Covid19

Liver Diseases

Eligibility:

All Genders

19+ years

Phase:

PHASE4

Brief Summary

Of patients admitted to an internal medicine ward with internistic diagnosis/es together with COVID-19, substantial proportion has elevated liver enzymes. silymarin / silibinin (milk thistle extract) ...

Detailed Description

According to the Bosch-Barrera et al. paper of 2021, silibinin in a daily dose of more than 1000 mg could improve clinical course of COVID-19 by its dual action: 1.direct inhibition of SARS-CoV-2 repl...

Eligibility Criteria

Inclusion

  • consecutive, adult, admitted to an internal medicine ward with internistic diagnosis, together with COVID-19, and elevated liver enzymes (any of AST, ALT, GGT, ALP), provided written informed consent

Exclusion

  • too sick - terminal illness (no potential for recovery); critical condition on admission requiring immediate tracheal intubation; or any extra-pulmonary organ failure; completely vaccinated against COVID19.

Key Trial Info

Start Date :

March 17 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2021

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04816682

Start Date

March 17 2021

End Date

December 30 2021

Last Update

August 3 2022

Active Locations (2)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (2 locations)

1

F.D.Roosevelt Teaching Hospital

Banská Bystrica, Slovakia, 97401

2

University Hospital Bratislava

Bratislava, Slovakia, 82101