Status:
NOT_YET_RECRUITING
Characterization of the Corneal Biomechanics of Patients Treated by Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) to Correct Myopia
Lead Sponsor:
University of Bern
Conditions:
Myopia
Eligibility:
All Genders
20-50 years
Brief Summary
This study aims to perform biomechanical tests on extracted CLEAR lenticles that are routinely discarded after surgery. The investigators also aim to perform Brillouin microscopy to get an in-vivo ass...
Detailed Description
Refractive surgery techniques such as laser in situ keratomileusis (LASIK), corneal lenticule extraction (SMILE/CLEAR) and photorefractive keratectomy (PRK) are becoming increasingly popular among myo...
Eligibility Criteria
Inclusion
- Patients scheduled for CLEAR procedures for myopia (range: \>-3D with an astigmatism \<0.25D) in the age group 20-50 years.
- Willing and able to return for scheduled follow-up examinations
- Able to provide written informed consent and follow study instructions in English or German
Exclusion
- Irregular corneal topo-/tomography (Asymmetry \>1.0D within the inner 5mm)
- Previous intraocular or corneal surgery of any kind in the eye to be treated, including any type of surgery for either refractive or therapeutic purposes.
- History of steroid-responsive rise in intraocular pressure, glaucoma, or preoperative intraocular pressure (IOP) \> 21 mmHg in either eye.
- History of diabetes, diagnosed autoimmune disease, connective tissue disease or clinically significant atopic syndrome.
Key Trial Info
Start Date :
June 1 2026
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04817592
Start Date
June 1 2026
End Date
December 31 2027
Last Update
September 19 2025
Active Locations (1)
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1
IROC AG
Zurich, Switzerland, 8002