Status:
UNKNOWN
Metabolomics Characterization of Biomarkers of Different Types of Myocardial Infarction in Different Time.
Lead Sponsor:
Shanghai 10th People's Hospital
Conditions:
Myocardial Infarction
Eligibility:
All Genders
20-76 years
Brief Summary
To find new biomarkers through Metabonomics Study of different types of myocardial infarction in Different Time.
Detailed Description
In recent years, with the deepening understanding of the mechanism of myocardial infarction, in addition to the early understanding of plaque rupture, plaque erosion and other mechanisms, studies have...
Eligibility Criteria
Inclusion
- The patient clearly had acute myocardial infarction. 2.The patient's serum cardiac markers (mainly troponin) were elevated (at least above the upper limit of 99% reference value) and accompanied by one of the following clinical indicators：
- Ischemic symptoms
- New ischemic ECG changes, new ST-T changes or left bundle branch block（LBBB）.
- Pathological Q wave formation in ECG
- Imaging evidence showed new loss of myocardial activity or new regional wall motion abnormalities.
- The thrombus was confirmed by coronary angiography. 3．The patient had chest pain symptoms, but coronary angiography showed normal coronary artery (such as intercostal neuralgia, cervical spondylosis, chest pain of unknown origin, etc.)
Exclusion
- Refusal to sign informed consent.
- Surgical treatment was performed in the last three months.
- Patients with a history of the following diseases or consider the diagnosis of the following diseases：Stress cardiomyopathy, myocarditis, pericarditis, pneumonia, pulmonary embolism, aortic dissection.
- Severe heart failure, grade IV cardiac function.
- Liver and kidney dysfunction.
- blood-borne diseases, including HIV / AIDS, hepatitis B, hepatitis C, etc.
- Patients with a history of malignancies, autoimmune diseases, severe infectious diseases and trauma.
- Previous history of myocardial infarction and stroke.
Key Trial Info
Start Date :
November 17 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04817748
Start Date
November 17 2020
End Date
May 1 2021
Last Update
March 26 2021
Active Locations (1)
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1
Yi Zhang
Shanghai, Shanghai Municipality, China