Status:
COMPLETED
Load-induced Changes in Glenohumeral Translation in Patients With Rotator Cuff Tear
Lead Sponsor:
University Hospital, Basel, Switzerland
Collaborating Sponsors:
Swiss National Science Foundation
Conditions:
Rotator Cuff Tear
Eligibility:
All Genders
20-85 years
Phase:
NA
Brief Summary
The study is to investigate the dose-response relationship between load-induced muscle activation (liMA) and load-induced glenohumeral translation (liTr) in patients with rotator cuff tears and asympt...
Detailed Description
This project is to test the overall hypothesis that rotator cuff tear affects glenohumeral translation and that this functional instability depends on additional load applied, on anatomical and morpho...
Eligibility Criteria
Inclusion
- We will examine a cohort of 75 subjects:
- Group 1: 25 patients with unilateral symptomatic rotator cuff tear between 45 and 85 years
- Group 2: 25 asymptomatic control subjects (age and sex distribution matching the patient group) Group 3: 25 sex matched young asymptomatic control subjects between 20 and 30 years
- Inclusion criteria patients:
- Diagnosed unilateral rotator cuff tear
- Partial or complete supraspinatus muscle tear
- With or without injury to other rotator cuff muscles
- Exclusion criteria patients:
- Prior operative treatment of the ipsilateral shoulder or elbow
- Clinical history or symptoms of the contralateral glenohumeral joint
- Range of motion \<30° in abduction and flexion
- Inclusion criteria asymptomatic control subjects:
- \- No previous known elbow and shoulder injury or symptoms
- Exclusion criteria asymptomatic control subjects:
- Clinical history of the glenohumeral joint
- Prior conservative or operative treatment of the shoulder or elbow
- Range of motion \<90° in abduction and flexion
- General exclusion criteria:
- Inability to provide informed consent
- Body mass index (BMI) \> 35 kg/m2 (Excessive skin movement)
- Neuromuscular disorders affecting upper limb movement
- Additional pathologies that influence the mobility of the shoulder joints
- Contraindications for MRI (e.g. neurostimulator and claustrophobia)
- Prior neuromuscular impairment (e.g. stroke)
- Diagnosed active rheumatic disorder
- Other major medical problems
- Pregnancy
- Patients currently enrolled in another experimental (interventional) protocol
Exclusion
Key Trial Info
Start Date :
May 4 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT04819724
Start Date
May 4 2021
End Date
December 31 2023
Last Update
April 12 2024
Active Locations (1)
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1
Department of Orthopaedics and Traumatology, University Hospital Basel
Basel, Switzerland, 4031