Status:
COMPLETED
Analysis of the Composition of the Vaginal Microbiota During IVF Treatment and Correlation With Serum Progesterone Level on the Day of Embryo Transfer
Lead Sponsor:
Centre Hospitalier Universitaire de Nīmes
Conditions:
IVF
Eligibility:
FEMALE
18-40 years
Brief Summary
The composition of the vaginal microbiota varies throughout a woman's life and is sensitive to hormonal and environmental factors. Specifically, hormonal treatments necessary in the medically assisted...
Eligibility Criteria
Inclusion
- Patient in round 1 or 2 of IVF or IVF-ICSI with transfer of a fresh embryo with a normal preimplantation assessment, without antibiotic treatment in the 3 months preceding the sample.
- The patient must have given their free and informed consent and signed the consent form
- The patient must be a member or beneficiary of a health insurance plan
Exclusion
- Use of antibiotics in the 3 months preceding the sample.
- Patient presenting an anomaly in the implantation assessment.
- Presence of uterine malformation, hydrosalpinx, chronic vaginosis.
- Patient undergoing a protocol to study endometrial receptivity.
- Patient of African American, African or Latin American origin (patients born to two parents of Hispanic origin) as people of African and Hispanic origin have a type IV flora vs people of Caucasian origins who have type I, II, III and V of the Ravel classification .
- Cancellation of the procedure for various reasons (stimulation failure, collection failure, fertilization failure or embryonic segmentation).
- Patient taking a freeze-all approach (freezing of the embryos) for various causes (risk of ovarian hyperstimulation, increase in progesterone, too thin endometrium, etc.).
- The subject is participating in a category 1 interventional study, or is in a period of exclusion determined by a previous study
- The subject refuses to sign the consent
- It is impossible to give the subject informed information
- The patient is under safeguard of justice or state guardianship
Key Trial Info
Start Date :
May 26 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 22 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04820985
Start Date
May 26 2021
End Date
April 22 2024
Last Update
April 26 2024
Active Locations (1)
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1
CHU de Nimes
Nîmes, France, 30029