Status:

COMPLETED

Role of AI in CE for the Identification of SB Lesions in Patients With Small Intestinal Bleeding.

Lead Sponsor:

Fondazione Poliambulanza Istituto Ospedaliero

Collaborating Sponsors:

Humanitas Hospital, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Conditions:

Iron Deficiency Anemia

Obscure Gastrointestinal Bleeding

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Capsule Endoscopy (CE) is a safe, patient friendly and easy procedure performed for the evaluation of gastrointestinal tract unable to be explored via conventional endoscopy. The most common indicatio...

Detailed Description

This is a multicenter, multinational, blinded prospective trial, involving a consecutive series of patients recruited by 12 European centers based on the indication of OGIB: * after negative upper an...

Eligibility Criteria

Inclusion

  • indication of OGIB:1)after negative upper and lower endoscopy; 2)France: after negative pregnancy test; 3)Hb cut-off male: \<13, female: \<12

Exclusion

  • Age \< 18 years old
  • Known or suspected intestinal obstruction
  • Non-steroidal anti-inflammatory drugs (twice weekly or more) during the 4 weeks preceding enrollment
  • Patient is expected to undergo MRI examination within 7 days after ingestion of the capsule
  • Patient with known gastrointestinal motility disorders
  • Subjects with known or suspected delayed gastric emptying
  • Patient suffers from any condition, such as swallowing problems, which precludes compliance with study and/or device instructions
  • Patient has any allergy or other known contraindication or intolerance to the medications used in the study
  • Patient has any condition, which precludes compliance with study and/or device instructions
  • Patient with any contraindication to take the bowel preparation product
  • Women who are either pregnant or nursing at the time of screening, or are of child- bearing potential and do not practice medically acceptable methods of contraception
  • Concurrent participation in another clinical trial using any investigational drug or device
  • Patient suffers from a life-threatening condition
  • Patients with history or clinical evidence of renal disease and/or previous clinically significant laboratory abnormalities of renal function parameters
  • Patients with pace-maker or implantable cardioverter
  • Patient did not sign informed consent
  • Endoscopic placement of the capsule

Key Trial Info

Start Date :

February 16 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2022

Estimated Enrollment :

137 Patients enrolled

Trial Details

Trial ID

NCT04821349

Start Date

February 16 2021

End Date

October 1 2022

Last Update

February 21 2024

Active Locations (1)

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Fondazione Poliambulanza

Brescia, Italy, 25124