Status:

UNKNOWN

Study of HEarT DiseAse and ImmuNiTy After COVID-19 in Ireland

Lead Sponsor:

Cardiovascular Research Institute Dublin

Conditions:

SARS-CoV Infection

Covid19

Eligibility:

All Genders

18+ years

Brief Summary

SETANTA study will investigate the incidence of cardiac abnormalities as assessed by cardiac magnetic resonance imaging in unselected patients after acute SARS-CoV-2 infection and correlation with imm...

Detailed Description

Approximately 100 participants from primary care will be enrolled via General Practitioner (GP) or Primary Care Centers in Dublin. A patient information sheet (PIS) will be made accessible to particip...

Eligibility Criteria

Inclusion

  • Patients 18 years or older
  • Written informed consent
  • Recent COVID-19 infection ≥ 6 weeks and ≤ 12 months before enrolment, as evidenced by positive reverse-transcriptase polymerase chain reaction (RT-PCR) SARS-CoV-2 swab

Exclusion

  • Prior history of myocarditis or ischemic heart disease
  • General contraindications for Magnetic Resonance Imaging e.g. Magnetic Resonance unsafe pacemaker, devices, implants etc.
  • Contraindication to gadolinium (estimated glomerular filtration rate \<30 ml/min)
  • Contraindication to Regadenoson, including cardiac conduction disease, asthma, seizures, pregnancy or breast-feeding
  • Inability to provide written informed consent, to fill out the safety questionnaire, or to fully cooperate with the scan and breath holds
  • Insufficient Cardiac Magnetic Resonance image quality

Key Trial Info

Start Date :

February 16 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 22 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04823182

Start Date

February 16 2021

End Date

September 22 2022

Last Update

September 24 2021

Active Locations (1)

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Cardiovascular Research Institute Dublin

Dublin, Ireland, D07 KWR1