Status:
ACTIVE_NOT_RECRUITING
Impact of a Process Optimizing the Decision to Continue or Stop Cancer Treatments in Patients With Advanced Non-small Cell Lung Cancer.
Lead Sponsor:
Institut Curie
Conditions:
Carcinoma, Non-Small-Cell Lung
Advanced Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Sequential comparative prospective interventional study evaluating the impact of the use of an optimization device of the decision of cancer treatment on aggressiveness of end of life care. Comparison...
Detailed Description
We propose to study the optimization of this decision process in an advanced Non-Small-Cell Lung Carcinoma (NSCLC) population, with a Performance Status (PS) ≥ 2 (median survival of approximately 3 mo...
Eligibility Criteria
Inclusion
- Histologically or cytologically proven non-small-cell lung carcinoma (NSCLC) including NSCLC with oncogene addiction.
- Stage IV or IIB/IIIC non irradiable (8th classification TNM, UICC 2015)
- Patient having completed at least one line of chemotherapy in the context of metastatic disease (or in the context of locoregional disease if the last chemotherapy was less than 6 months ago).
- ECOG Performance Status ≥ 2.
- Age ≥ 18.
- Written informed consent.
- Patient capable, according to the investigator, to comply with the requirements of the study.
Exclusion
- Small Cell Lung Cancer (including mixed forms).
- Patient with NSCLC for whom a decision has already been made to permanently discontinue all systemic cancer treatment.
- Impossible follow up for geographical, social or psychological reason.
- Inability to answer a questionnaire (language or neurological barrier).
- Patient under guardianship.
- Patient being treated in a therapeutic trial.
- Patient not covered by social security. -
Key Trial Info
Start Date :
September 24 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 23 2027
Estimated Enrollment :
364 Patients enrolled
Trial Details
Trial ID
NCT04823377
Start Date
September 24 2021
End Date
September 23 2027
Last Update
November 28 2025
Active Locations (25)
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1
CH Abbeville
Abbeville, France, 80142
2
CH du Pays d'Aix
Aix-en-Provence, France, 13616
3
CHU Amiens - Hôpital Sud
Amiens, France, 80054
4
CHU Angers
Angers, France, 49933