Status:
UNKNOWN
Cardiopulmonary Effect of Mechanical Ventilation in Children With Right Ventricular Hypertrophy
Lead Sponsor:
Limin Zhu
Conditions:
Heart-lung Interaction
Right Ventricular Hypertrophy
Eligibility:
All Genders
3-3 years
Phase:
NA
Brief Summary
Neurally adjusted ventilatory assist (NAVA) is a new mode of mechanical ventilation that delivers ventilatory assist in proportion to neural effort. The investigators hope to compare the hemodynamic a...
Detailed Description
In the patients suffered from congenital heart disease with right ventricular hypertrophy, the preload of the heart will be influenced by the variation of the intrathoracic pressure. The cardiopulmona...
Eligibility Criteria
Inclusion
- Patients underwent surgical repair of right ventricular hypertrophic congenital heart disease
- Obtain informed consent signed by parents
Exclusion
- Significant residual shunt (more than 2mm), residual obstruction of right ventricular outflow tract (RVOT) or A-V valve insufficiency.
- Hemodynamic instability (whose inotropic score more than 20);
- Significant bleed (whose chest drainage more than 5ml/kg/h);
- Failed to insert the PiCCO catheter
- Dysfunction and abnormal of esophage;
- Inclusion in other research protocol
Key Trial Info
Start Date :
February 25 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04825054
Start Date
February 25 2021
End Date
December 31 2021
Last Update
April 1 2021
Active Locations (2)
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1
Cardiac intensive care unit, Department of cardiothoracic vascular surgery, Shanghai Children's Medical Center, Medical college of Shanghai Jiaotong University
Shanghai, Shanghai Municipality, China, 200127
2
Shanghai Children's Medical Center, Shanghai Jiaotong Universiry School of Medicine
Shanghai, Shanghai Municipality, China, 200127