Status:

UNKNOWN

Hyperkinetic Movements in Patients With Disease of Motor Neurons and Their Response to Treatment With Nusinersen

Lead Sponsor:

University Medical Centre Ljubljana

Conditions:

Tremor

Involuntary Movements

Eligibility:

All Genders

Brief Summary

Hyperkinetic movement disorders in patients with diseases of motor neurons will be studied. Patients with spinal muscular atrophy (SMA) and motor neuron disease patients will be studied. Involuntary ...

Detailed Description

Background: Minipolymyoclonus and tremor are frequently mentioned as part of the clinical picture of spinal muscular atrophy, but the precise mechanism of the occurrence of tremor and minipolymyoclonu...

Eligibility Criteria

Inclusion

  • Genetically proven SMA patients treated with Nusinersen
  • ''clinically definite ALS'' or ''clinically probable ALS'' or ''clinically probable ALS - laboratory supported'' according to the revised El Escorial diagnostic criteria or diagnosis of PMA or PLS

Exclusion

  • No.

Key Trial Info

Start Date :

October 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 30 2021

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT04825119

Start Date

October 1 2017

End Date

July 30 2021

Last Update

April 1 2021

Active Locations (1)

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1

University Medical Centre Ljubljana

Ljubljana, Slovenia, 1000