Status:

UNKNOWN

Subclinical Diabetes Confirmed by 75gm-OGTT Influence on the Prognosis of Decompensated Cirrhosis

Lead Sponsor:

Yonsei University

Conditions:

Liver Cirrhosis

Eligibility:

All Genders

18+ years

Brief Summary

Disorders of glucose metabolism, such as impaired glucose intolerance (IGT) and diabetes mellitus (DM), frequently occur in cirrhosis. However, it has been underestimated when fasting plasma glucose (...

Eligibility Criteria

Inclusion

  • Liver cirrhosis
  • Admitted to a hospital

Exclusion

  • Previously confirmed DM
  • Being treated for DM
  • Standard risk factors of T2DM, such as high body mass index and family history of diabetes
  • Symptoms of DM, such as increased thirst and the need to urinate
  • Either hepatocellular carcinoma or other malignancy
  • Hepatic failure or uncontrolled decompensation \[that is, refractory ascites or active variceal hemorrhage\]
  • Significant illnesses such as sepsis that may have interfered with glucose metabolism
  • Pancreatic dysfunction such as acute/chronic pancreatitis that may have affected glucose metabolism.

Key Trial Info

Start Date :

January 2 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 30 2021

Estimated Enrollment :

1015 Patients enrolled

Trial Details

Trial ID

NCT04828512

Start Date

January 2 2007

End Date

December 30 2021

Last Update

April 2 2021

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