Status:

ACTIVE_NOT_RECRUITING

Real-Time fMRI to Enhance Interventions That Change Delay Discounting

Lead Sponsor:

Virginia Polytechnic Institute and State University

Collaborating Sponsors:

Fralin Biomedical Research Institute

Conditions:

Alcohol Use Disorder (AUD)

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

The investigators will use real-time fMRI neurofeedback to enhance participants' ability to control their temporal window, and hence their ability to modulate delay discounting and alcohol valuation.

Detailed Description

Based on 8 years of experience recruiting alcohol users into studies of comparable length and complexity, the investigators anticipate that 92% of consented participants will be eligible (i.e., random...

Eligibility Criteria

Inclusion

  • demonstrate high-risk or harmful drinking (AUDIT\>15)
  • be 21 years of age or older
  • have a desire to quit or cut down on their drinking, but do not have proximate plans to enroll in treatment for AUD during the study period

Exclusion

  • meeting moderate to severe DSM-5 criteria for substance-use disorders other than alcohol or nicotine
  • having a current diagnosis of any psychotic disorder
  • having a history of seizure disorders or traumatic brain injury
  • having any contraindication for participation in the MRI sessions
  • reporting current pregnancy or lactation

Key Trial Info

Start Date :

January 13 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 31 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04828577

Start Date

January 13 2023

End Date

August 31 2025

Last Update

January 13 2025

Active Locations (1)

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Fralin Biomedical Research Institute at VTC

Roanoke, Virginia, United States, 24016