Status:
RECRUITING
The "MyoThrombus" Study
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
NHS Lothian
Conditions:
Left Ventricular Thrombus
Thrombosis
Eligibility:
All Genders
40+ years
Brief Summary
Left ventricular thrombus is a recognised complication of acute myocardial infarction, associated with stroke, recurrent myocardial infarction and adverse cardiac remodelling. The prevention, treatmen...
Detailed Description
Cardiovascular thrombotic conditions were estimated to account for 1 in 4 deaths worldwide in 2010 and are the leading cause of global mortality. Thrombosis begins with damage to the vascular wall. Ph...
Eligibility Criteria
Inclusion
- Male or females over the age of 40 with recent (within 21±2 days) acute type 1 anterior myocardial infarction
- Provision of informed consent prior to any study specific procedures
Exclusion
- Inability or unwilling to give informed consent.
- Concomitant use of anticoagulation agents (warfarin, apixaban, edoxaban, rivaroxaban, dabigatran or SC/IV Heparin) (Cohort 1 only)
- Unable to tolerate the supine position
- Impaired renal function with eGFR of \<30 mL/min/1.73m2
- Severe or significant comorbidity
- Women who are pregnant or breastfeeding • Severe claustrophobia
Key Trial Info
Start Date :
December 2 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04829825
Start Date
December 2 2020
End Date
December 1 2025
Last Update
June 24 2025
Active Locations (1)
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1
Royal Infirmary Edinburgh
Edinburgh, United Kingdom