Status:

UNKNOWN

Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives

Lead Sponsor:

D'Or Institute for Research and Education

Conditions:

Channelopathies

Eligibility:

All Genders

Brief Summary

several genes have been associated with ion channel diseases, but a large number of families do not yet have an identified genetic cause. There is a lack of information on the genetic characteristics ...

Detailed Description

Inherited arrhythmias are characterized by variable expressiveness and incomplete penetrance. Extensive genotype-phenotype studies are needed to elucidate the genetic basis of these diseases. There ar...

Eligibility Criteria

Inclusion

  • Patients from Rede D'or São Luiz and their relatives
  • Patients whit arrhythmia and their relatives
  • Presence of inheritance pattern of causal genetic variants or those associated with phenotypes jointly defined as cardiac channelopathies and their relatives

Exclusion

  • None

Key Trial Info

Start Date :

January 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2024

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04832126

Start Date

January 1 2018

End Date

July 31 2024

Last Update

April 6 2021

Active Locations (1)

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1

D'Or Institute for Research and Education (IDOR)

Rio de Janeiro, Brazil, 22281-100