Status:
COMPLETED
Childhood Apraxia of Speech: Experience Dependent Changes Induced by Treatment
Lead Sponsor:
IRCCS Fondazione Stella Maris
Collaborating Sponsors:
Ministry of Health, Italy
Conditions:
Childhood Apraxia of Speech
Eligibility:
All Genders
4-16 years
Brief Summary
Childhood Apraxia of Speech (CAS) is a severe speech-language disorder whose aetiological, neuroanatomical correlates are largely unknown. Furthermore, little is known about the neuroplastic effects i...
Detailed Description
Background: Childhood Apraxia of Speech (CAS) is a severe speech-language disorder whose etiological, neuroanatomical and genetic correlates are largely unknown. In this trial the effects of an innova...
Eligibility Criteria
Inclusion
- Diagnosis of idiopathic CAS based on the presence of specific diagnostic features of apraxia of speech (see ASHA and Strand et al's criteria) and on a comprehensive clinical and neurological assessment.
- Non-verbal IQ within the normal range at standardized tests of intelligence.
- Normal structural brain MRI.
- Acquisition of parents' informed consent to the execution of behavoiural and neuroradiological assessment at baseline and to perform speech/language treatment.
Exclusion
- Orofacial structural abnormalities.
- Known pathologies of neurological, neurometabolical and genetic etiologies.
- Audiological deficits.
- Epilepsy.
- Intellectual disability.
- Autism spectrum disorder.
Key Trial Info
Start Date :
September 30 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 30 2023
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04832503
Start Date
September 30 2018
End Date
March 30 2023
Last Update
October 24 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
IRCCS Fondazione Stella Maris
Tirrenia, Tuscany, Italy, 56128