Status:
RECRUITING
Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas
Lead Sponsor:
Leiden University Medical Center
Collaborating Sponsors:
HollandPTC
Varian Medical Systems
Conditions:
Bone Neoplasm of Vertebral Column
Chordoma
Eligibility:
All Genders
50+ years
Brief Summary
Rationale: Chordomas and chondrosarcomas located in the axial skeleton are malignant neoplasms of bone. These tumors share the same clinical challenges, as the effect of the disease is more a function...
Eligibility Criteria
Inclusion
- Histologically diagnosed with primary or recurrent chordoma or chondrosarcoma in the axial skeleton (clivus, spine and sacrum)
- Accepted for standard proton beam therapy
Exclusion
- Diagnosis other than chordoma or chondrosarcoma is made.
- Patient refuses (parts) of the standard treatment protocol.
- Patient refuses MRI due to claustrophobia.
- Patient not suitable for MRI due to the presence of MRI incompatible implants.
- Incapacitated patients.
- Patient doesn't allow coded data to be used for analysis.
- Patient is under 50 years of age.
- Lesion size less than 1cm.
- Patients with WHO 3 and higher.
Key Trial Info
Start Date :
February 2 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04832620
Start Date
February 2 2021
End Date
December 1 2027
Last Update
November 18 2023
Active Locations (2)
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1
HollandPTC
Delft, South Holland, Netherlands, 2629 JH
2
LUMC
Leiden, South Holland, Netherlands, 2333 ZA