Status:

UNKNOWN

Study on the Relationship Between Neutrophil-mediated Thrombocytopenia and the Condition and the Course of Disease in Patients With HFRS

Lead Sponsor:

First Affiliated Hospital Xi'an Jiaotong University

Conditions:

Hemorrhagic Fever With Renal Syndrome

Eligibility:

All Genders

18+ years

Brief Summary

Thrombocytopenia is an important pathological feature of HFRS(Hemorrhagic Fever With Renal Syndrome, HFRS). However, the cause of thrombocytopenia in HFRS is not yet fully understood. Neutrophils, as ...

Eligibility Criteria

Inclusion

  • Age ≥18 years;
  • Clinical diagnosis meets the diagnostic criteria of the national HFRS prevention and treatment plan (Hantavirus-specific IgM antibody is positive). The classification and staging standards of HFRS patients are based on the "Expert Consensus of Shaanxi Province on Diagnosis and Treatment of Hemorrhagic Fever with Renal Syndrome".

Exclusion

  • Age \<18 years;
  • Have a history of kidney disease;
  • Have a history of liver disease;
  • Have a history of malignant tumor;
  • Receive dialysis treatment before admission;
  • Combined with hypertension, coronary heart disease and diabetes history;
  • Combined with HIV infection and patients with autoimmune diseases and pregnancy.

Key Trial Info

Start Date :

October 9 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 28 2024

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT04834713

Start Date

October 9 2020

End Date

February 28 2024

Last Update

September 9 2021

Active Locations (1)

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1

First Affiliated Hospital of Xian Jiaotong university

Xi'an, Shaanxi, China, 710061