Status:
ACTIVE_NOT_RECRUITING
Transorbital Ultrasound and Other Markers for Prognosis Prediction After Cardiac Arrest
Lead Sponsor:
University Hospital Pilsen
Collaborating Sponsors:
Na Homolce Hospital
Conditions:
Cardiac Arrest
Eligibility:
All Genders
18+ years
Brief Summary
In sudden cardiac arrest patients with return of spontaneous circulation, brain damage is one of the main determinants of short-term mortality and poor prognosis (CPC 3-5). It is important to properly...
Detailed Description
Additional relevant MeSH terms: cardiac arrest, cardiovascular diseases, optic nerve sheath diameter.
Eligibility Criteria
Inclusion
- age of 18 years or older
- out of hospital cardiac arrest of non-traumatic cause with CPR and subsequent ROSC
- Glasgow coma scale (GCS) ≤ 7 or sedation 30 minutes after ROSC achievment
Exclusion
- unavailable first measurment of the optic nerve sheath diameter (ONSD) measured by transorbital ultrasonography 24±6 hours after ROSC achievement
- refractory cardiac arrest
- craniocerebral injury
- intracranial tumor
- active intracranial bleeding
- haemorrhagic stroke and/or subarachnoid haemorrhage in the last 3 months
- facial trauma affecting the eye area
- active neuroendocrine tumor, small cell lung cancer, non-small cell lung
- CPC 3-5 before cardiac arrest
- sclerosis multiplex and/or optic neuritis of other etiology
Key Trial Info
Start Date :
January 4 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2025
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04838418
Start Date
January 4 2021
End Date
June 1 2025
Last Update
January 15 2025
Active Locations (1)
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1
University Hospital Plzen
Pilsen, Czechia