Status:

UNKNOWN

Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria

Lead Sponsor:

MEDSI Clinical Hospital 1, ICU

Conditions:

Pneumonia, Ventilator-Associated

Pneumonia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Secondary infections remain a major cause of mortality in critically ill patients, mainly because of high prevalence of multidrug-resistant microorganisms. Therefore strategies aimed to reduce the inc...

Detailed Description

Single-center prospective interventional parallel study. During the first period of the study patients will receive standard therapy. During the second period the SDD protocol will be implemented in a...

Eligibility Criteria

Inclusion

  • Patients with expected MV for more than 24 hours

Exclusion

  • Moribund condition and expected death within 24 hours
  • Malignancy (excluding primary CNS tumors)
  • Patients transferred from other hospitals who were mechanically ventilated for more than 24 hours (including NIV)

Key Trial Info

Start Date :

May 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2023

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04839653

Start Date

May 1 2021

End Date

April 1 2023

Last Update

June 8 2021

Active Locations (1)

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1

MEDSI Clinical Hospital 1

Moscow, Russia, 143442