Status:

COMPLETED

Normal Values of Parameters of Thrombin Generation in Function of Different Tissue Factor Concentrations

Lead Sponsor:

Centre Hospitalier Universitaire de Saint Etienne

Conditions:

Healthy Volunteers

Eligibility:

All Genders

18-50 years

Brief Summary

The thrombin generation assay (TGA) is a good tool for measuring clot formation in plasma.TGA using Calibrated Automated Thrombography method, enables the quantification of thrombin concentrations in ...

Detailed Description

The thrombin generation assay (TGA) is a good tool for measuring clot formation in plasma. TGA using Calibrated Automated Thrombography method, enables the quantification of thrombin concentrations in...

Eligibility Criteria

Inclusion

  • Patient beneficiary or affiliated to Social security system
  • Consent signed

Exclusion

  • Personal or family history (parents, brothers, sisters) of hemorrhage
  • Personal or family history (parents, brothers, sisters) of thrombosis before 45 years old
  • Taking an anti-inflammatory or an aspirin one week before the sampling
  • Current take of an anticoagulant or antiaggregant treatment
  • Surgery within previous month before the sampling
  • Chronic pathology responsible of an inflammatory syndrome
  • Episode of viral or bacterial infections
  • Known HIV or Hepatitis C Virus (HCV) infection
  • Participation in a therapeutic clinical trial

Key Trial Info

Start Date :

April 23 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 30 2023

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT04842084

Start Date

April 23 2021

End Date

March 30 2023

Last Update

December 1 2023

Active Locations (1)

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CHU de Saint-Etienne - Service d'Hématologie

Saint-Etienne, France, 42055