Status:
UNKNOWN
Negative Pressure Ventilation-rehabilitation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Chronic Obstructive Pulmonary Disease
Acute Exacerbation of COPD
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
This investigator-initiated, prospective, single center, randomized, controlled clinical trial enrolled patients with stable Global Initiative for Chronic Obstructive Lung Disease stage II-IV chronic ...
Detailed Description
Pulmonary rehabilitation (PR) has been suggested to be positive effects on 6 min walking distance (6MWD), muscle force, cycle exercise endurance time, and quality of life. However, the literature stil...
Eligibility Criteria
Inclusion
- Diagnosis of COPD ((post-bronchodilation forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) \<0.7)
- Optimal medical treatment according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD)) at least 3 months before screening
Exclusion
- abnormalities of the thorax or the lung other than COPD,
- acute exacerbation within one month
- obesity with a body-mass index (BMI) ≥35 kg/m²,
- malignant co-morbidities, severe heart failure (New York Heart Association stage IV), unstable angina, severe arrhythmias, neuromuscular diseases and/or impairment of basal brain nerve function with disturbed swallowing and choking and impaired general condition that could preclude regular follow-up visits.
Key Trial Info
Start Date :
April 8 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04843696
Start Date
April 8 2021
End Date
December 31 2024
Last Update
April 13 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chang Gung Memorial Hospital
Taoyuan District, Taiwan, 333