Status:
RECRUITING
Observational Study on Skeletal Ewing's Sarcoma
Lead Sponsor:
Italian Sarcoma Group
Conditions:
Ewing Sarcoma of Bone
Eligibility:
All Genders
Up to 49 years
Brief Summary
Observational prospective trial aimed to collect the collect demographic, clinical, surgical, pathological and molecular characteristics and treatment from patients affected by skeletal Ewing Sarcoma
Detailed Description
The Ewing sarcoma treatment is based on chemotherapy, surgery and radiotherapy. Chemotherapy, performed with a combination of several drugs, is given as primary treatment before surgery. Surgical int...
Eligibility Criteria
Inclusion
- Diagnosis of Ewing's sarcoma of the bone
- Diagnosis of Ewing-like sarcoma (round cell sarcoma with fusion of the EWSR1 gene with others not of the ETS family, sarcoma with CIC rearrangement or sarcoma with BCOR rearrangement)
- Diagnosis of extraosseous Ewing's sarcoma for patients
- Age at diagnosis \<50 years
- Assessment of the extent of the disease at onset in accordance with the European Society of Medical Oncology guidelines
- Patients or parents oe guardians of minors who have given their written informed consent to participate in the study
Exclusion
- 1\. Presence of comorbid factors who can compromise the compliance of the treatment plan or the evaluation of the outcomes, including but not limited to organ pathologies that contraindicate the use of chemotherapy and psychological or social conditions that do not allow for adequate compliance treatment or adequate follow-up
Key Trial Info
Start Date :
June 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 25 2028
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04845893
Start Date
June 1 2021
End Date
May 25 2028
Last Update
January 2 2026
Active Locations (19)
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1
Istituto Clinico Humanitas
Rozzano, MI, Italy, 20089
2
Centro di Riferimento Oncologico - Unit of Medical Oncology
Aviano, Pordenone, Italy, 33081
3
I.R.C.C. - Unit of Medical Oncology
Candiolo, Torino, Italy, 10060
4
Azienda ospedaliero universitaria consorziale policlinico - bari
Bari, Italy, 70124