Status:

COMPLETED

Dental Implants in Patients Under Oral Anticoagulant Therapy

Lead Sponsor:

Jorge Ernesto Aguilar

Conditions:

Oral Anticoagulant Therapy

Eligibility:

All Genders

21-75 years

Phase:

NA

Brief Summary

This study evaluated the outcomes in the post-operative recovery following dental implant surgery in patients who continued on oral anticoagulated therapy (OAT) with warfarin. The primary outcome of t...

Detailed Description

The aim of this study was compare: 1) the frequency of immediate and short term postoperative bleeding using tranexamic acid (TXAg), bismuth subgallate (BSg) or dry gauze (DGg) as local hemostatic 2) ...

Eligibility Criteria

Inclusion

  • Subjects:
  • Systemically healthy.
  • Healthy periodontal tissues or well-controlled periodontal health.
  • In need of a maximum of two dental implants per hemiarcade,
  • Showing ≥8mm bone height and ≥6 horizontal bone width.
  • Needing a maximum of two surgical procedures.
  • Who had written consent from the referring service to undergo the surgical procedure.

Exclusion

  • Subjects:
  • Requiring implant placement immediately after extraction.
  • Systemic disease contraindicating implant surgery.
  • Mental disability preventing them from complying with the protocol.
  • Hematological, metabolic, autoimmune or bone diseases.
  • Hepatic alterations or receiving medication affecting liver function.
  • Receiving corticoid therapy, chemotherapy, or anticoagulant therapy within 10 days prior to the surgery.
  • Taking antibiotics that interact with oral anticoagulants.
  • Requiring vertical or periosteal incisions.
  • Requiring bone regeneration strategy.
  • When treatment involved placing an implant in more than one hemiarcade, the corresponding surgeries were scheduled 30 days apart.

Key Trial Info

Start Date :

March 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2019

Estimated Enrollment :

71 Patients enrolled

Trial Details

Trial ID

NCT04846114

Start Date

March 1 2016

End Date

June 1 2019

Last Update

October 12 2022

Active Locations (1)

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Masters in Dental Implantology (MIO) program at the University of Salvador (USAL)-Argentine Dental Association

Buenos Aires, Argentina, 1125