Status:
COMPLETED
Adherence to HIV Treatment Postpartum: The Implications of Transitions Among Women Living With HIV in South Africa
Lead Sponsor:
Brown University
Collaborating Sponsors:
University of Cape Town
National Institute of Mental Health (NIMH)
Conditions:
HIV
Pregnancy Related
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
Despite high levels of adherence motivation during pregnancy, HIV treatment adherence and engagement in care is difficult for women in the postpartum period. Supporting women during the transition fro...
Detailed Description
Prevention of mother-to-child transmission (PMTCT) efforts have reduced the rates of vertical transmission to 2.7%, however, optimal antiretroviral therapy (ART) adherence remains a difficult goal to ...
Eligibility Criteria
Inclusion
- 18 years of age or older
- HIV positive status (based on clinic records)
- Confirmed pregnant (based on clinic records) and estimated to be 23-34 weeks gestation (clinic records or self-report)
- Currently prescribed ART
- Planning on remaining a resident of Cape Town for at least 6 months postpartum
- Ability to speak isiXhosa or English
- Able to provide informed consent
Exclusion
- Failure to meet any of the inclusion criteria
- Significant pre-existing psychiatric comorbidity at enrolment that may impact ability to consent according to the judgement of study personnel (including cognitive impairment or known psychotic disorder) Note: mothers will not be withdrawn from the study following foetal complications or death
Key Trial Info
Start Date :
April 12 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2023
Estimated Enrollment :
62 Patients enrolled
Trial Details
Trial ID
NCT04846569
Start Date
April 12 2021
End Date
September 30 2023
Last Update
February 28 2024
Active Locations (1)
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1
Gugulethu Community Health Centre
Cape Town, South Africa