Status:
COMPLETED
Pleiotropic Role of TRPV1 in Psoriasis Inflammation
Lead Sponsor:
University Hospital, Brest
Conditions:
Inflammation; Skin
Psoriasis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Widely expressed in the sensory nerve endings of the skin, Transient Receptor Potential Vanilloid 1 (TRPV1) is a receptor that plays an important role in the perception of pain and pruritus but also i...
Detailed Description
Each patient will have a sample taken in the dermatology department: * 4 skin biopsies * A blood sample. Patients with psoriasis will be recruited from the dermatology department. There will be no f...
Eligibility Criteria
Inclusion
- Patients over 18 years old with psoriasis, with or without itching (pruritus).
- Presence of lesional and non lesional zones, in unexposed areas and surface area (outside the face and folds) large enough to allow the biopsies to be performed
- Patients who have given written consent
Exclusion
- Patients with physical or psychological incapacity to sign consent
- Patients not covered by the Social Security system
- Patients with topical treatments for psoriasis,
- Patients with systemic treatments for psoriasis,
- Patients allergic to lidocaine
- Patients over the age of majority who are subject to legal protection or who are unable to give consent
- Patients deprived of liberty by a judicial or administrative decision
- Pregnant women, parturients and breastfeeding mothers
Key Trial Info
Start Date :
December 22 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 24 2024
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT04848194
Start Date
December 22 2021
End Date
January 24 2024
Last Update
March 28 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
TALAGAS
Brest, France, 29200