Status:
UNKNOWN
Novel Time-efficient Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure
Lead Sponsor:
University of Colorado, Boulder
Conditions:
Blood Pressure
Endothelial Dysfunction
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
Above-normal systolic blood pressure (SBP), defined as SBP \>/= 120 mmHg, is the major modifiable risk factor for cardiovascular disease, stroke, cognitive decline/dementia, and other chronic health p...
Eligibility Criteria
Inclusion
- Age 50 years and older
- Ability to provide informed consent
- Willing to accept random assignment to condition
- Resting systolic blood pressure 120 mmHg or greater
- Body mass index \<40 kg/m2
- Weight stable in the prior 3 months (\<2 kg weight change) and willing to remain weight stable throughout the study
- Mini-mental state exam score of 24 or higher
- No change in blood pressure medications or other medications (prescriptions or dosing) in the prior 3 months and willing to maintain current medication regimen
- Free from clinical disease with the exception of hypertension
Exclusion
- Younger than age 50
- History of uncontrolled hypertension (systolic blood pressure \>180 mmHg and/or diastolic blood pressure \>120 mmHg)
- Current smoker
- Abnormal blood pressure response to exercise (drop in systolic blood pressure below resting levels or systolic blood pressure \>260 mmHg or diastolic blood pressure \>115 mmHg)
- Regular vigorous aerobic/endurance exercise (\>4 bouts/week, \>30 min/bout at a workload \>6 METS)
Key Trial Info
Start Date :
May 7 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2025
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT04848675
Start Date
May 7 2021
End Date
May 31 2025
Last Update
November 2 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Colorado Boulder
Boulder, Colorado, United States, 80309