Status:
RECRUITING
Treatment Strategy of Human Gamma Globulin on the Therapy for Intensively Ill Children With Inflammatory Storm
Lead Sponsor:
Children's Hospital of Fudan University
Conditions:
Critical Illness
Sepsis, Severe
Eligibility:
All Genders
29-18 years
Brief Summary
The inflammatory storm in critically ill patients releases cytokines, causing systemic immune damage, which may be an important cause of multiple organ failure and even death. Inflammatory storms exac...
Detailed Description
In severe infective patients who survive the initial inflammatory storm, the immune response often evolves toward a state of immunosuppression, which contributes to increased mortality and severe seco...
Eligibility Criteria
Inclusion
- children hospitalized in PICU of Children's Hospital of Fudan University
- Children With Severe Infection Complicated With Inflammatory Storm
Exclusion
- discharge within 48 hours
- patients without informed consent
- incomplete clinical and demographic data
Key Trial Info
Start Date :
October 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04850456
Start Date
October 1 2024
End Date
December 31 2025
Last Update
February 20 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Children's Hospital of Fudan University
Shanghai, Shanghai Municipality, China
2
Children's Hospital of Fudan University
Shanghai, China, 201102